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Genetic elevation of Sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila
Duchenne muscular dystrophy is a lethal genetic disease characterized by the loss of muscle integrity and function over time. Using Drosophila, we show that dystrophic muscle phenotypes can be significantly suppressed by a reduction of wunen, a homolog of lipid phosphate phosphatase 3, which in high...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Company of Biologists
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3513996/ https://ncbi.nlm.nih.gov/pubmed/23154413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087791 |
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