A pilot safety trial investigating a vector-based vaccine targeting CEA in combination with radiotherapy in patients with gastrointestinal malignancies metastatic to the liver

OBJECTIVE: Previous studies have demonstrated the ability of non-lethal doses of radiation to alter the phenotype of tumor cells to facilitate immune mediated killing. This pilot study evaluated the tolerability of a vector-based vaccine targeting CEA in combination with radiation therapy in patient...

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Detalhes bibliográficos
Main Authors: Gulley, James L., Madan, Ravi A., Tsang, Kwong-Yok, Arlen, Philip M., Camphausen, Kevin, Mohebtash, Mahsa, Kamrava, Mitchell, Schlom, Jeffrey, Citrin, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513964/
https://ncbi.nlm.nih.gov/pubmed/21871012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2011.615741
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