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Mipomersen and other therapies for the treatment of severe familial hypercholesterolemia

Familial hypercholesterolemia (FH) is an autosomal dominant condition with a population prevalence of one in 300–500 (heterozygous) that is characterized by high levels of low-density lipoprotein (LDL) cholesterol, tendon xanthomata, and premature atherosclerosis and coronary heart disease (CHD). FH...

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Detalhes bibliográficos
Main Authors: Bell, Damon A, Hooper, Amanda J, Watts, Gerald F, Burnett, John R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513909/
https://ncbi.nlm.nih.gov/pubmed/23226021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/VHRM.S28581
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