Differing Patterns of Circulating Regulatory T-Cells and Myeloid Derived Suppressor Cells in Metastatic Melanoma Patients Receiving Anti-CTLA4 Antibody and Interferon-α or TLR-9 Agonist and GM-CSF with Peptide Vaccination

Changes in the biomarkers of host suppressor immune response were evaluated in patients with melanoma enrolled on two trials. Two similar cohorts of patients participating in the two studies were evaluated. The first (IFN/treme) tested interferon-α2b and tremelimumab in metastatic melanoma and repor...

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Bibliographic Details
Main Authors: Tarhini, Ahmad A, Butterfield, Lisa H., Shuai, Yongli, Gooding, William E., Kalinski, Pawel, Kirkwood, John M
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513773/
https://ncbi.nlm.nih.gov/pubmed/23090079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318272569b
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