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Human CST has independent functions during telomere duplex replication and C-strand fill-in

Human CST (CTC1-STN1-TEN1) is an RPA-like complex that is needed for efficient replication through the telomere duplex and genome-wide replication restart after fork stalling. Here we show that STN1/CST has a second function in telomere replication during G-overhang maturation. Analysis of overhang...

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Autors principals: Wang, Feng, Stewart, Jason A., Kasbek, Christopher, Zhao, Yong, Wright, Woodring E., Price, Carolyn M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513692/
https://ncbi.nlm.nih.gov/pubmed/23142664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.007
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