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Mitomycin C-treated Trypanosoma cruzi in vaccination of mice: induction of immunosuppression but not protection.

Attempts to immunize susceptible hosts against infection with Trypanosoma cruzi have generally not met with a high degree of success. In the present study, we used the antimetabolite mitomycin C to produce nonreplicating, attenuated culture forms of T. cruzi. Attempts to immunize highly susceptible...

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Опубликовано в::Infect Immun
Главные авторы: Tarleton, R L, Kuhn, R E, Cunningham, D S
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1981
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6783545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.31.2.693-697.1981
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