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Mitomycin C-treated Trypanosoma cruzi in vaccination of mice: induction of immunosuppression but not protection.

Attempts to immunize susceptible hosts against infection with Trypanosoma cruzi have generally not met with a high degree of success. In the present study, we used the antimetabolite mitomycin C to produce nonreplicating, attenuated culture forms of T. cruzi. Attempts to immunize highly susceptible...

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Hlavní autoři: Tarleton, R L, Kuhn, R E, Cunningham, D S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC351365/
https://ncbi.nlm.nih.gov/pubmed/6783545
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