Deficits in Transcriptional Regulators of Cortical Parvalbumin Neurons in Schizophrenia

OBJECTIVE: In schizophrenia, alterations within the prefrontal cortical GABA system appear to be most prominent in neurons that contain parvalbumin or somatostatin but not calretinin. The transcription factors Lhx6 and Sox6 play critical roles in the specification, migration, and maturation of parva...

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Autors principals: Volk, David W., Matsubara, Takurou, Li, Siyu, Sengupta, Elizabeth J., Georgiev, Danko, Minabe, Yoshio, Sampson, Allan, Hashimoto, Takanori, Lewis, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513625/
https://ncbi.nlm.nih.gov/pubmed/22983435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2012.12030305
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