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Characterisation of Ilomastat for Prolonged Ocular Drug Release

We are developing tablet dosage forms for implantation directly into the subconjunctival space of the eye. The matrix metalloproteinase inhibitor, ilomastat, has previously been shown to be efficacious at suppressing scarring following glaucoma filtration surgery (GFS). We report on the physical cha...

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Detalhes bibliográficos
Main Authors: Parkinson, Gary, Gaisford, Simon, Ru, Qian, Lockwood, Alastair, Khalili, Ashkan, Sheridan, Rose, Khaw, Peng T., Brocchini, Steve, Fadda, Hala M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513442/
https://ncbi.nlm.nih.gov/pubmed/22903888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9832-1
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