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An Ilomastat-CD Eye Drop Formulation to Treat Ocular Scarring

PURPOSE: The purpose of this study was to develop a topical matrix metalloproteinase inhibitor preparation for antiscarring therapy. METHODS: The broad spectrum matrix metalloproteinase inhibitor ilomastat was formulated using 2-hydroxypropyl-β-cyclodextrin in aqueous solution. In vitro activity of...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Mohamed-Ahmed, Abeer H. A., Lockwood, Alastair, Li, He, Bailly, Maryse, Khaw, Peng T., Brocchini, Steve
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713897/
https://ncbi.nlm.nih.gov/pubmed/28692737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21377
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