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Expression of AS3MT alters transcriptional profiles in human urothelial cells exposed to arsenite

Inorganic arsenic (iAs) is an environmental toxicant and human carcinogen. The enzymatic methylation of iAs that is catalyzed by arsenic (+3 oxidation state)-methyltransferase (AS3MT) generates reactive methylated intermediates that contribute to the toxic and carcinogenic effects of iAs. We have sh...

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書誌詳細
主要な著者: Hester, SD, Drobná, Z, Andrews, DMK, Liu, J, Waalkes, MP, Thomas, DJ, Stýblo, M
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513271/
https://ncbi.nlm.nih.gov/pubmed/19411561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0960327109102368
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