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shRNA Silencing of AS3MT Expression Minimizes Arsenic Methylation Capacity of HepG2 Cells

Several methyltransferases have been shown to catalyze the oxidative methylation of inorganic arsenic (iAs) in mammalian species. However, the relative contributions of these enzymes to the overall capacity of cells to methylate iAs have not been characterized. Arsenic (+3 oxidation state) methyltra...

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Библиографические подробности
Главные авторы: Drobná, Zuzana, Xing, Weibing, Thomas, David J., Stýblo, Miroslav
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329798/
https://ncbi.nlm.nih.gov/pubmed/16841956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060076u
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