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shRNA Silencing of AS3MT Expression Minimizes Arsenic Methylation Capacity of HepG2 Cells

Several methyltransferases have been shown to catalyze the oxidative methylation of inorganic arsenic (iAs) in mammalian species. However, the relative contributions of these enzymes to the overall capacity of cells to methylate iAs have not been characterized. Arsenic (+3 oxidation state) methyltra...

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Hlavní autoři: Drobná, Zuzana, Xing, Weibing, Thomas, David J., Stýblo, Miroslav
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329798/
https://ncbi.nlm.nih.gov/pubmed/16841956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060076u
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