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Ofatumumab: a novel monoclonal anti-CD20 antibody

Ofatumumab, a novel humanized monoclonal anti-CD20 antibody, was recently approved by the FDA for the treatment of fludarabine and alemtuzumab refractory chronic lymphocytic leukemia (CLL). Ofatumumab effectively induces complement-dependent cytotoxicity (CDC) in vitro, and recent studies demonstrat...

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Bibliografiske detaljer
Hovedforfatter: Lin, Thomas S
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513208/
https://ncbi.nlm.nih.gov/pubmed/23226042
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