Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection

A number of studies have suggested B7-H1, a B7 family member, inhibits T cell responses. Therefore, its expression on nonlymphoid tissues has been proposed to prevent T cell–mediated tissue destruction. To test this hypothesis, we generated transgenic mice that expressed B7-H1 on pancreatic islet β...

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Hlavní autoři: Subudhi, Sumit K., Zhou, Ping, Yerian, Lisa M., Chin, Robert K., Lo, James C., Anders, Robert A., Sun, Yonglian, Chen, Lieping, Wang, Yang, Alegre, Maria-Luisa, Fu, Yang-Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC351315/
https://ncbi.nlm.nih.gov/pubmed/14991067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419210
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