NK-cell activation by LIGHT triggers tumor-specific CD8(+) T-cell immunity to reject established tumors

Natural killer (NK) cells are generally reported as innate effector cells for killing virally infected and transformed cells. It is unclear how NK cells evoke adaptive immunity to eradicate tumors. We now demonstrate that the TNF superfamily member, LIGHT, known as TNFSF14 and a T-cell costimulatory...

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Detalhes bibliográficos
Main Authors: Fan, Zusen, Yu, Ping, Wang, Yang, Wang, Yugang, Fu, May Lynne, Liu, Wenhua, Sun, Yonglian, Fu, Yang-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895398/
https://ncbi.nlm.nih.gov/pubmed/16223768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3485
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