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115 Caspase-4 Plays a Role in the Activation of the Cryopyrin/NLRP3 Inflammasome
BACKGROUND: The inflammasome is a multi-protein complex which regulates the activation of caspase-1. This activation results in the cleavage and secretion of the IL-1β super family cytokines, IL-1β, IL-18, and IL-33. NLR family-pyrin domain containing- 3 (NLRP3) is a nucleotide binding domain-leucin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
World Allergy Organization Journal
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3512947/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.WOX.0000411860.83535.b0 |
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