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B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
Failure of immunization with the HIV-1 envelope to induce broadly neutralizing antibodies against conserved epitopes is a major barrier to producing a preventive HIV-1 vaccine. Broadly neutralizing monoclonal antibodies (BnAbs) from those subjects who do produce them after years of chronic HIV-1 inf...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3512202/ https://ncbi.nlm.nih.gov/pubmed/22565972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2197 |
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