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Locating a Lipid at the Portal to the Lipoxygenase Active Site

Lipoxygenase enzymes initiate diverse signaling pathways by specifically directing oxygen to different carbons of arachidonate and other polyunsaturated acyl chains, but structural origins of this specificity have remained unclear. We therefore determined the nature of the lipoxygenase interaction w...

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Main Authors: Gaffney, Betty J., Bradshaw, Miles D., Frausto, Stephen D., Wu, Fayi, Freed, Jack H., Borbat, Peter
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512035/
https://ncbi.nlm.nih.gov/pubmed/23200047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.10.002
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