Atypical angiopoietin-like protein that regulates ANGPTL3

Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL family member, ANGPTL8, whic...

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Autori principali: Quagliarini, Fabiana, Wang, Yan, Kozlitina, Julia, Grishin, Nick V., Hyde, Rhonda, Boerwinkle, Eric, Valenzuela, David M., Murphy, Andrew J., Cohen, Jonathan C., Hobbs, Helen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511699/
https://ncbi.nlm.nih.gov/pubmed/23150577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217552109
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