Multiple receptor tyrosine kinases promote the in vitro phenotype of metastatic human osteosarcoma cell lines

The survival rate for osteosarcoma patients with localized disease is 70% and only 25% for patients with metastases. Therefore, novel therapeutic and prognostic tools are needed. In this study, extensive screening and validation strategies identified Axl, EphB2, FGFR2, IGF-1R and Ret as specific rec...

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Autores principales: Rettew, A N, Young, E D, Lev, D C, Kleinerman, E S, Abdul-Karim, F W, Getty, P J, Greenfield, E M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511679/
https://ncbi.nlm.nih.gov/pubmed/23552467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.34
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