Lipopolysaccharide Potentiates Polychlorinated Biphenyl-induced Disruption of the Blood–Brain Barrier via TLR4/IRF-3 Signaling

Exposure to polychlorinated biphenyls (PCBs) is associated with numerous adverse health effects. Although the main route of exposure to PCBs is through the gastrointestinal tract, little is known about the contribution of the gut to the health effects of PCBs. We hypothesize that PCBs can disrupt in...

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Main Authors: Choi, Jeong June, Choi, Yean Jung, Chen, Lei, Zhang, Bei, Eum, Sung Yong, Abreu, Maria T, Toborek, Michal
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511608/
https://ncbi.nlm.nih.gov/pubmed/22906770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2012.08.001
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