MCUR1 is an Essential Component of Mitochondrial Ca(2+) Uptake that Regulates Cellular Metabolism

Ca(2+) flux across the mitochondrial inner membrane regulates bioenergetics, cytoplasmic Ca(2+) signals and activation of cell death pathways(1–11). Mitochondrial Ca(2+) uptake occurs at regions of close apposition with intracellular Ca(2+) release sites (12–14), driven by the inner membrane voltage...

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Main Authors: Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick, Chandramoorthy, Harish C., Irrinki, Krishna M., Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E., Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J. Kevin, Madesh, Muniswamy
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511605/
https://ncbi.nlm.nih.gov/pubmed/23178883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2622
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