MCUR1 is an Essential Component of Mitochondrial Ca(2+) Uptake that Regulates Cellular Metabolism

Ca(2+) flux across the mitochondrial inner membrane regulates bioenergetics, cytoplasmic Ca(2+) signals and activation of cell death pathways(1–11). Mitochondrial Ca(2+) uptake occurs at regions of close apposition with intracellular Ca(2+) release sites (12–14), driven by the inner membrane voltage...

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Hauptverfasser: Mallilankaraman, Karthik, Cárdenas, César, Doonan, Patrick, Chandramoorthy, Harish C., Irrinki, Krishna M., Golenár, Tünde, Csordás, György, Madireddi, Priyanka, Yang, Jun, Müller, Marioly, Miller, Russell, Kolesar, Jill E., Molgó, Jordi, Kaufman, Brett, Hajnóczky, György, Foskett, J. Kevin, Madesh, Muniswamy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511605/
https://ncbi.nlm.nih.gov/pubmed/23178883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2622
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