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MicroRNA 218 Mediates the Effects of Tbx5a Over-Expression on Zebrafish Heart Development

tbx5, a member of the T-box gene family, encodes one of the key transcription factors mediating vertebrate heart development. Tbx5 function in heart development appears to be exquisitely sensitive to gene dosage, since both haploinsufficiency and gene duplication generate the cardiac abnormalities a...

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Detalhes bibliográficos
Main Authors: Chiavacci, Elena, Dolfi, Luca, Verduci, Lorena, Meghini, Francesco, Gestri, Gaia, Evangelista, Alberto Mercatanti Monica, Wilson, Stephen W., Cremisi, Federico, Pitto, Letizia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511548/
https://ncbi.nlm.nih.gov/pubmed/23226307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050536
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