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Assessment of Genotype Imputation Performance Using 1000 Genomes in African American Studies
Genotype imputation, used in genome-wide association studies to expand coverage of single nucleotide polymorphisms (SNPs), has performed poorly in African Americans compared to less admixed populations. Overall, imputation has typically relied on HapMap reference haplotype panels from Africans (YRI)...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3511547/ https://ncbi.nlm.nih.gov/pubmed/23226329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050610 |
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