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Structural Requirements for the Procoagulant Activity of Nucleic Acids

Nucleic acids, especially extracellular RNA, are exposed following tissue- or vessel damage and have previously been shown to activate the intrinsic blood coagulation pathway in vitro and in vivo. Yet, no information on structural requirements for the procoagulant activity of nucleic acids is availa...

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Bibliografische gegevens
Hoofdauteurs: Gansler, Julia, Jaax, Miriam, Leiting, Silke, Appel, Bettina, Greinacher, Andreas, Fischer, Silvia, Preissner, Klaus T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511531/
https://ncbi.nlm.nih.gov/pubmed/23226277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050399
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