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Phase II Trial of Sorafenib in Combination with Carboplatin and Paclitaxel in Patients with Metastatic Uveal Melanoma: SWOG S0512

BACKGROUND: Sorafenib, a multikinase inhibitor of cell proliferation and angiogenesis, inhibits the mitogen-activated protein kinase pathway that is activated in most uveal melanoma tumors. This phase II study was conducted by the SWOG cooperative group to evaluate the efficacy of sorafenib in combi...

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מידע ביבליוגרפי
Main Authors: Bhatia, Shailender, Moon, James, Margolin, Kim A., Weber, Jeffrey S., Lao, Christopher D., Othus, Megan, Aparicio, Ana M., Ribas, Antoni, Sondak, Vernon K.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511501/
https://ncbi.nlm.nih.gov/pubmed/23226204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048787
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