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A 5-bp Insertion in Mip Causes Recessive Congenital Cataract in KFRS4/Kyo Rats

We discovered a new cataract mutation, kfrs4, in the Kyoto Fancy Rat Stock (KFRS) background. Within 1 month of birth, all kfrs4/kfrs4 homozygotes developed cataracts, with severe opacity in the nuclei of the lens. In contrast, no opacity was observed in the kfrs4/+ heterozygotes. We continued to ob...

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Bibliografische gegevens
Hoofdauteurs: Watanabe, Kei, Wada, Kenta, Ohashi, Tomoko, Okubo, Saki, Takekuma, Kensuke, Hashizume, Ryoichi, Hayashi, Jun-Ichi, Serikawa, Tadao, Kuramoto, Takashi, Kikkawa, Yoshiaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511373/
https://ncbi.nlm.nih.gov/pubmed/23226368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050737
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