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A novel missense mutation of Mip causes semi-dominant cataracts in the Nat mouse

Major intrinsic protein of lens fiber (MIP) is one of the proteins essential for maintaining lens transparency while also contributing to dominant cataracts in humans. The Nodai cataract (Nat) mice harbor a spontaneous mutation in Mip and develop early-onset nuclear cataracts. The Nat mutation is a...

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Detalhes bibliográficos
Publicado no:Exp Anim
Main Authors: Takahashi, Gou, Hasegawa, Sayaka, Fukutomi, Yukiko, Harada, Chihiro, Furugori, Masamune, Seki, Yuta, Kikkawa, Yoshiaki, Wada, Kenta
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Association for Laboratory Animal Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543248/
https://ncbi.nlm.nih.gov/pubmed/28442635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.17-0012
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