Anti-CD25 Treatment Depletes Treg Cells and Decreases Disease Severity in Susceptible and Resistant Mice Infected with Paracoccidioides brasiliensis

Regulatory T (Treg) cells are fundamental in the control of immunity and excessive tissue pathology. In paracoccidioidomycosis, an endemic mycosis of Latin America, the immunoregulatory mechanisms that control the progressive and regressive forms of this infection are poorly known. Due to its modula...

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Main Authors: Felonato, Maíra, Pina, Adriana, de Araujo, Eliseu Frank, Loures, Flávio V., Bazan, Silvia B., Feriotti, Cláudia, Calich, Vera L. G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511355/
https://ncbi.nlm.nih.gov/pubmed/23226464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051071
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