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Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with Paracoccidioides brasiliensis.

Regulatory T (Treg) cells are fundamental in the control of immunity and excessive tissue pathology. In paracoccidioidomycosis, an endemic mycosis of Latin America, the immunoregulatory mechanisms that control the progressive and regressive forms of this infection are poorly known. Due to its modula...

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Bibliografske podrobnosti
Main Authors: Maíra Felonato, Adriana Pina, Eliseu Frank de Araujo, Flávio V Loures, Silvia B Bazan, Cláudia Feriotti, Vera L G Calich
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3511355?pdf=render
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