Protective Role of STAT3 in NMDA and Glutamate-Induced Neuronal Death: Negative Regulatory Effect of SOCS3

The present study investigates the involvement of the IL-6 family of cytokines, activation of the transcription factor Signal Transducer and Activator of Transcription-3 (STAT3), and the role of Suppressor Of Cytokine Signaling-3 (SOCS3) in regulating excitotoxic neuronal death in vitro. Biochemical...

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Bibliographic Details
Main Authors: Park, Keun W., Nozell, Susan E., Benveniste, Etty N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511325/
https://ncbi.nlm.nih.gov/pubmed/23226414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050874
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