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Mitochondrial STAT3 is negatively regulated by SOCS3 and upregulated after spinal cord injury

Suppressor of cytokine signaling-3 (SOCS3) expression is induced by the Janus kinase (JAK)-signal transducer and activator of transcription 3 (STAT3) signaling pathway. SOCS3 then acts as a feedback inhibitor of JAK-STAT signaling. Previous studies have shown that knocking down SOCS3 in spinal cord...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Park, Keun Woo, Lin, Ching-Yi, Benveniste, Etty N., Lee, Yu-Shang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035219/
https://ncbi.nlm.nih.gov/pubmed/27502766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.08.002
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