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Oncolytic adenovirus armed with IL-24 Inhibits the growth of breast cancer in vitro and in vivo

BACKGROUND: Interleukin-24 (IL-24) is a cytokine that belongs to the IL-10 family. It can selectively induce cancer cell apoptosis which has been utilized as a cancer gene therapy strategy. METHODS: A recombinant type five adenovirus containing IL-24 gene (designated CNHK600-IL24) was constructed, w...

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Detalhes bibliográficos
Main Authors: Zhu, Wei, Wei, Lai, Zhang, Hongwei, Chen, Junxue, Qin, Xinyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511263/
https://ncbi.nlm.nih.gov/pubmed/22640485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-51
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