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Impact of sustained RNAi-mediated suppression of cellular cofactor Tat-SF1 on HIV-1 replication in CD4+ T cells

BACKGROUND: Conventional anti-HIV drug regimens targeting viral enzymes are plagued by the emergence of drug resistance. There is interest in targeting HIV-dependency factors (HDFs), host proteins that the virus requires for replication, as drugs targeting their function may prove protective. Report...

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Detalhes bibliográficos
Main Authors: Green, Victoria A, Arbuthnot, Patrick, Weinberg, Marc S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511259/
https://ncbi.nlm.nih.gov/pubmed/23153325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-272
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