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Cellular cofactors affecting hepatitis C virus infection and replication

Recently identified hepatitis C virus (HCV) isolates that are infectious in cell culture provide a genetic system to evaluate the significance of virus–host interactions for HCV replication. We have completed a systematic RNAi screen wherein siRNAs were designed that target 62 host genes encoding pr...

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Detalles Bibliográficos
Autores principales: Randall, Glenn, Panis, Maryline, Cooper, Jacob D., Tellinghuisen, Timothy L., Sukhodolets, Karen E., Pfeffer, Sebastien, Landthaler, Markus, Landgraf, Pablo, Kan, Sherry, Lindenbach, Brett D., Chien, Minchen, Weir, David B., Russo, James J., Ju, Jingyue, Brownstein, Michael J., Sheridan, Robert, Sander, Chris, Zavolan, Mihaela, Tuschl, Thomas, Rice, Charles M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937561/
https://ncbi.nlm.nih.gov/pubmed/17616579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704894104
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