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Complement is dispensable for neurodegeneration in Niemann-Pick disease type C
BACKGROUND: The immune system has been implicated in neurodegeneration during development and disease. In various studies, the absence of complement (that is, C1q deficiency) impeded the elimination of apoptotic neurons, allowing survival. In the genetic lysosomal storage disease Niemann-Pick C (NPC...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3511250/ https://ncbi.nlm.nih.gov/pubmed/22985423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-216 |
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