Gonococci with mutations to low-level penicillin resistance exhibit increased sensitivity to the oxygen-independent bactericidal activity of human polymorphonuclear leukocyte granule extracts.

Gonococci which cause disseminated gonococcal infection are nearly always highly penicillin sensitive, in contrast to many isolates causing uncomplicated gonorrhea. We questioned whether any of the known chromosomal mutations to low-level penicillin resistance might adversely affect virulence. The p...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Daly, J A, Lee, T J, Spitznagel, J K, Sparling, P F
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6802762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.35.3.826-833.1982
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