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Gonococci with mutations to low-level penicillin resistance exhibit increased sensitivity to the oxygen-independent bactericidal activity of human polymorphonuclear leukocyte granule extracts.

Gonococci which cause disseminated gonococcal infection are nearly always highly penicillin sensitive, in contrast to many isolates causing uncomplicated gonorrhea. We questioned whether any of the known chromosomal mutations to low-level penicillin resistance might adversely affect virulence. The p...

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Publicat a:Infect Immun
Autors principals: Daly, J A, Lee, T J, Spitznagel, J K, Sparling, P F
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1982
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351122/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6802762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.35.3.826-833.1982
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