A network of genetic repression and derepression specifies projection fates in the developing neocortex

Neurons within each layer in the mammalian cortex have stereotypic projections. Four genes—Fezf2, Ctip2, Tbr1, and Satb2—regulate these projection identities. These genes also interact with each other, and it is unclear how these interactions shape the final projection identity. Here we show, by gen...

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Detalhes bibliográficos
Main Authors: Srinivasan, Karpagam, Leone, Dino P., Bateson, Rosalie K., Dobreva, Gergana, Kohwi, Yoshinori, Kohwi-Shigematsu, Terumi, Grosschedl, Rudolf, McConnell, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511157/
https://ncbi.nlm.nih.gov/pubmed/23144223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216793109
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