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Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
Broadly neutralizing HIV antibodies (bNAbs) can recognize carbohydrate-dependent epitopes on gp120. In contrast to previously characterized glycan-dependent bNAbs that recognize high-mannose N-glycans, PGT121 binds complex-type N-glycans in glycan microarrays. We isolated the B-cell clone encoding P...
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| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3511153/ https://ncbi.nlm.nih.gov/pubmed/23115339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217207109 |
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