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Peptides presenting the binding site of human CD4 for the HIV-1 envelope glycoprotein gp120

Based on the structure of the HIV-1 glycoprotein gp120 in complex with its cellular receptor CD4, we have designed and synthesized peptides that mimic the binding site of CD4 for gp120. The ability of these peptides to bind to gp120 can be strongly enhanced by increasing their conformational stabili...

詳細記述

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書誌詳細
主要な著者: Meier, Julia, Kassler, Kristin, Sticht, Heinrich, Eichler, Jutta
フォーマット: Artigo
言語:Inglês
出版事項: Beilstein-Institut 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511023/
https://ncbi.nlm.nih.gov/pubmed/23209523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.214
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