1,25-Dihydroxyvitamin D3 Suppresses Telomerase Expression and Human Cancer Growth through MicroRNA-498

Telomerase is an essential enzyme that counteracts the telomere attrition accompanying DNA replication during cell division. Regulation of the promoter activity of the gene encoding its catalytic subunit, the telomerase reverse transcriptase, is established as the dominant mechanism conferring the h...

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Bibliographische Detailangaben
Hauptverfasser: Kasiappan, Ravi, Shen, Zheng, Tse, Anfernee K-W, Jinwal, Umesh, Tang, Jinfu, Lungchukiet, Panida, Sun, Yuefeng, Kruk, Patricia, Nicosia, Santo V., Zhang, Xiaohong, Bai, Wenlong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510828/
https://ncbi.nlm.nih.gov/pubmed/23055531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.407189
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