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Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010)

INTRODUCTION: Farnesyl pyrophosphosphate synthase (FPPS (also known as farnesyl diphosphate synthase, FDPS)) is one of the key enzymes involved in the mevalonate pathway and as such is widely expressed. FPPS modulators, specifically FPPS inhibitors, are useful in treating a number of diseases, inclu...

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Détails bibliographiques
Auteurs principaux: Sun, Shuting, McKenna, Charles E.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510766/
https://ncbi.nlm.nih.gov/pubmed/21702715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543776.2011.593511
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