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Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010)

INTRODUCTION: Farnesyl pyrophosphosphate synthase (FPPS (also known as farnesyl diphosphate synthase, FDPS)) is one of the key enzymes involved in the mevalonate pathway and as such is widely expressed. FPPS modulators, specifically FPPS inhibitors, are useful in treating a number of diseases, inclu...

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Detalles Bibliográficos
Main Authors: Sun, Shuting, McKenna, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510766/
https://ncbi.nlm.nih.gov/pubmed/21702715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543776.2011.593511
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