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Target mRNA inhibition by oligonucleotide drugs in man

Oligonucleotide delivery in vivo is commonly seen as the principal hurdle to the successful development of oligonucleotide drugs. In an analysis of 26 oligonucleotide drugs recently evaluated in late-stage clinical trials we found that to date at least half have demonstrated suppression of the targe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lightfoot, Helen L., Hall, Jonathan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510500/
https://ncbi.nlm.nih.gov/pubmed/22989709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks861
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