Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions

The androgen receptor (AR) is a ligand-inducible transcription factor that mediates androgen action in target tissues. Upon ligand binding, the AR binds to thousands of genomic loci and activates a cell-type specific gene program. Prostate cancer growth and progression depend on androgen-induced AR...

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Bibliografske podrobnosti
Main Authors: Decker, Keith F., Zheng, Dali, He, Yuhong, Bowman, Tamara, Edwards, John R., Jia, Li
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Gene Regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510497/
https://ncbi.nlm.nih.gov/pubmed/23019221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks888
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