Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy

The bone marrow (BM) is a major organ of breast cancer (BC) dormancy and a common source of BC resurgence. Gap junctional intercellular communication (GJIC) between BC cells (BCCs) and BM stroma facilitates dormancy. This study reports on a hierarchy of BCCs with the most immature subset (Oct4(hi)/C...

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Detalhes bibliográficos
Main Authors: Patel, Shyam A., Ramkissoon, Shakti H., Bryan, Margarette, Pliner, Lillian F., Dontu, Gabriela, Patel, Prem S., Amiri, Sohrab, Pine, Sharon R., Rameshwar, Pranela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510468/
https://ncbi.nlm.nih.gov/pubmed/23205268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00906
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