Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-A peptides

Breast cancer remains the cancer with the highest mortality among women in the United States. Peptides derived from the oncogenic Tac1 gene (full transcript: βPPT-A) stimulate the proliferation of breast cancer cells (BCCs) via seven-transmembrane G protein-coupled neurokinin 1 (NK1) and NK2 recepto...

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Hlavní autoři: Patel, Hiral J., Ramkissoon, Shakti H., Patel, Prem S., Rameshwar, Pranela
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297665/
https://ncbi.nlm.nih.gov/pubmed/16291810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506351102
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