Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

Pathological studies on Parkinson's disease (PD) patients suggest that PD pathology progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous system. We have previously shown that environmental toxins acting locally on the ENS mimic this PD-like pathology...

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Main Authors: Pan-Montojo, Francisco, Schwarz, Mathias, Winkler, Clemens, Arnhold, Mike, O'Sullivan, Gregory A., Pal, Arun, Said, Jonas, Marsico, Giovanni, Verbavatz, Jean-Marc, Rodrigo-Angulo, Margarita, Gille, Gabriele, Funk, Richard H. W., Reichmann, Heinz
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510466/
https://ncbi.nlm.nih.gov/pubmed/23205266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00898
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